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KMID : 0363320170380040443
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Journal of Korean Oriental Internal Medicine
2017 Volume.38 No. 4 p.443 ~ p.454
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An Overview of the Applicability of Oryung-san as an Antihypertensive Agent
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Jeong Ju-Hui
Kang Ki-Wan
Kang Ja-Yeon
Yoon Jee-Hyun
Choi Yoo-Min
Kim Hong-Jun
Sun Seung-Ho
Jang In-Soo
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Abstract
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Objectives: This study assessed the application of Oryung-san (Wuling-san or Gorei-san), a common diuretic in traditional medicine, as an antihypertensive agent.
Methods: Experimental studies of the pharmacological properties of Oryung-san, including diuretic action and lowering effects on blood pressure, and toxicology and clinical trials were reviewed.
Results: In pharmacology, various, relatively safe diuretics are used to lower blood pressure and are the oldest and most studied antihypertensive agents. Despite many new drug approvals, antihypertensive diuretics are frequently used in Korea and Japan where high levels of sodium uptake are common. Oryung-san has been demonstrated to have diuretic, antihypertensive, and nephroprotective effects.
Conclusions: Oryung-san might be effective for lowering blood pressure based on the results of this literature review. Further evaluations and large-scale clinical trials of Oryung-san to treat primary hypertension are warranted.
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KEYWORD
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herbal medication, hypertension, blood pressure, Korean medicine, Oryung-san, Wuling-san, Gorei-san
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